Jump to Section 1. Background 2. Methods 2.1. Study design and approval 2.2. Sampling and preanalytical procedures 2.3. Biomarker analysis 2.4. Statistical analysis 3. Results 3.1. Normalization of center-specific effects 3.2. Influence of age, sex, and APOE genotype 3.3. Clinical and pathological stratification 3.4. Sex-specific effects on pathology-based comparisons 3.5. Age-dependent pathological trajectories 3.6. Immune markers associated with PD staging independent of aging 4. Discussion 4.1. Key findings 4.2. Reproducibility of findings 4.3. Influence of biological confounders 4.4. Limitations 4.5. Outlook Supplementary Data References
For the purpose of conciseness, an overview of previous findings for comparison, including the respective literature, is given in Supplementary Table 1 Supplementary Table 1 .
YKL-40: Within this study, YKL-40…
Read more…