Multicenter Alzheimer’s and Parkinson’s disease immune biomarker verification study

Jump to Section1. Background2. Methods  2.1. Study design and approval  2.2. Sampling and preanalytical procedures  2.3. Biomarker analysis  2.4. Statistical analysis3. Results  3.1. Normalization of center-specific effects  3.2. Influence of age, sex, and APOE genotype  3.3. Clinical and pathological stratification  3.4. Sex-specific effects on pathology-based comparisons  3.5. Age-dependent pathological trajectories  3.6. Immune markers associated with PD staging independent of aging4. Discussion  4.1. Key findings  4.2. Reproducibility of findings  4.3. Influence of biological confounders  4.4. Limitations  4.5. OutlookSupplementary DataReferences

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