Research led by Queen Mary University of London and the University of Seville around one protein’s role in regulating brain inflammation could improve our understanding of neurodegenerative diseases.
The findings of a study involving mice are published today in the scientific journal Cell Reports.
The lead authors, Dr. Miguel Burguillos from the University of Seville and Dr. Miguel Branco from Queen Mary, found that when the brain is under inflammatory conditions a protein called TET2 regulates the immune response generated in the brain’s immune cells (or microglia).
Although neuroinflammation has an important beneficial role in fighting infection and responding to…