Scientists discover a potential way to repair synapses damaged in Alzheimer’s disease

While newly approved drugs for Alzheimer’s show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory. What is needed are more treatment options targeted to restore memory, said Buck Assistant Professor Tara Tracy, PhD, the senior author of a study that proposes an alternate strategy for reversing the memory problems that accompany Alzheimer’s disease and related dementias.

Since most current research on potential treatments for Alzheimer’s focuses on reducing the toxic proteins, such as tau and amyloid beta, that accumulate in the brain as the disease progresses, the team veered away from this route to explore an alternative. “Rather than trying to reduce toxic proteins in the brain, we are trying to reverse the damage caused by Alzheimer’s disease to restore memory,” said Tracy. The findings appear in the…

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