Advancing Alzheimer’s Research Through Neuroimaging

Leighton Hinkley, PhD, first author of “Distinct neurophysiology during nonword repetition in logopenic and non-fluent variants of primary progressive aphasia” in Human Brain Mapping uses advanced imaging techniques to better understand neurodegenerative diseases. The research focused on Primary Progressive Aphasia (PPA), a condition within the Alzheimer’s disease spectrum. In a recent interview Hinkley, a neuroscientist at the University of California, San Francisco (UCSF), explains his team’s neuroimaging research.

The Motivation Behind the Study

“The study is the first of its kind,” shares Hinkley, noting that it was prompted by a collaboration with experts in the Department of Neurology at UCSF’s Memory and Aging Center, who have long grappled with the challenge of diagnosing diseases like PPA based solely on behavioral observations. In PPA, different subtypes can be…

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