Association between cardiovascular diseases and dementia among various age groups: a population-based cohort study in older adults

After adjustment for other CV risk factors or diseases, diabetes, stroke, HF and AF remained significantly associated with an increased dementia risk in all aged groups studied. The strength of these associations decreased with advanced age for diabetes, stroke and HF. From 66 to over 90 years, the increased dementia risk associated with respectively diabetes, stroke and HF passed from 1.84, 3.54, 2.08 folds in the younger age group to 1.20, 1.13, 1.16 among patients ≥ 90 years old. The association of AF and dementia was more or less stable with advanced ages. Our results suggest that preventing diabetes, stroke, HF and AF before early advanced age is crucial to prevent dementia. So, cognitive function assessment should be performed in the routine clinical management of patients with CV risk factors, especially in early ages, and a decline in cognitive function should…