Researchers at Tohoku University have discovered that there are two parallel processes involved in memory formation when a mouse performs a motor learning task. One process occurs during training and is called online learning, while the other happens during the resting period and is called offline learning. Online learning can be boosted or reduced by manipulating glial activity, but offline learning remains unaffected by these manipulations. Understanding the cellular mechanisms underlying these independent parallel memory formation processes may lead to the development of efficient rehabilitation after strokes, dementia treatment, or realizing extended intelligence.
The findings were detailed in the journal Glia on June 26, 2023.
We have long been aware that performance may not improve much during training, but increase the next day. Alternatively, excelling during training may not…