A mouse study by Kristin Stanford, a physiology and cell biology researcher with The Ohio State University College of Medicine at the Wexner Medical Center, provides new ways to determine how maternal and paternal exercise improve metabolic health of offspring.
Laurie Goodyear of the Joslin Diabetes Center and Harvard Medical School co-led the study, published online in the journal Diabetes.
This study used mice to evaluate how their lifestyles — eating fatty foods vs. healthy and exercising vs. not — affected the metabolites of their offspring.
Metabolites are substances made or used when the body breaks down food, drugs or chemicals, or its own fat or muscle tissue. This process, called metabolism, makes energy and the materials needed for growth, reproduction and maintaining health. Metabolites can serve as disease markers, particularly for type 2 diabetes and cardiovascular…