Study finds that EPA inhibits an important signaling molecule, thereby reducing chronic pain — ScienceDaily

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities. Additionally, recent studies have demonstrated its therapeutic effects in reducing mortality risk after myocardial infarction, improving insulin resistance, reducing blood lipid levels, and inhibiting platelet aggregation. Omega-3 PUFAs have also been shown to decrease inflammatory responses following COVID-19 infection. Despite the wide spectrum of its therapeutic effects, the molecular target(s) and the underlying mechanism of EPA’s action remain elusive.