
Advanced imaging technology developed by Yale researchers has helped them confirm that the destruction of brain synapses underlies the cognitive deficits experienced by patients with Alzheimer’s disease, according to a study published Feb. 17 in the journal Alzheimer’s & Dementia.
For many years, scientists have assumed that the loss of connections between brain cells caused Alzheimer’s-related symptoms, including memory loss, but actual evidence of the role of synaptic loss had been limited to a small number of brain biopsies and post-mortem brain exams conducted on patients with moderate…