An alternative hypothesis based on synaptic alterations

Alzheimer's disease: an alternative hypothesis based on synaptic alterations
Human hippocampal brain section from an Alzheimer’s disease patient showing amyloid precursor protein (green) clustering around amyloid plaques (purple and red). Credit: Gael Barthet

New research published today in Alzheimer’s & Dementia, the journal of the Alzheimer’s Association could explain why neurons fail to communicate effectively in people with Alzheimer’s disease (AD). The study conducted by researchers in the laboratory of Christophe Mulle at the Interdisciplinary Institute of Neuroscience in Bordeaux opens a new research path to establish the molecular mechanism causing AD.

Despite intense efforts in , there is no treatment to cure or…

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