Indiana University School of Medicine researchers are making new discoveries about the pathological changes in people who have inherited Alzheimer’s disease versus developing the disease sporadically. These findings could lead to new ways of preventing and treating the disease.
In a new paper published in Science, researchers from the MRC Laboratory of Molecular Biology in Cambridge, England, United Kingdom and IU School of Medicine detail new findings about senile plaques, which are made up of a peptide called Amyloid-β 42 (Aβ 42). The study shows for the first time that the structure of the Aβ 42 filaments is different in sporadic…
