Newswise — LEXINGTON, Ky. (Dec. 15, 2021) – Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer’s disease.
Thus far, no effective treatments for Alzheimer’s disease (AD) are available. New approaches to preventing the progression of this devastating neurological disease are desperately needed.
The laboratories of Ramon Sun, Ph.D., assistant professor of neuroscience, UK College of Medicine and Markey Cancer Center, and Matthew Gentry, Ph. D., professor of molecular and cellular biochemistry and director of the Lafora Epilepsy Cure Initiative, UK College of Medicine, developed a novel imaging method to identify the specific patterns of sugar molecules that are attached to proteins within a tissue. The form of sugar attachment that they…
