A drug used to treat agitation in people with dementia is no more effective than a placebo, and might even increase mortality, according to a new study.
The research, led by the University of Plymouth and published in The Lancet, has shown that antidepressant mirtazapine offered no improvement in agitation for people with dementia—and was possibly more likely to be associated with mortality than no intervention at all.
Agitation is a common symptom of dementia, characterized by inappropriate verbal, vocal or motor activity, and often involves physical and verbal aggression. Non-drug patient-centered care is the first…