A drug already used to treat high blood pressure could be re-purposed as the first treatment to tackle a type of vascular dementia caused by damaged and ‘leaky’ small blood vessels in the brain, according to research part-funded by the British Heart Foundation and published today in the Journal of Clinical Investigation.
High blood pressure is known to be the main risk factor in developing vascular dementia. However, the way that high blood pressure damages the small blood vessels, causing them to narrow and restrict blood flow to specific areas of the brain, has been unknown. The effectiveness of different types of blood…