Participants
The study participants comprised 63 patients clinically diagnosed with cognitive impairment due to DLB, as reported in our previous study8, and 49 cognitively healthy controls. Subjects underwent neurological examination, neuropsychological tests, Mini-Mental State Examination (MMSE), 3 Tesla magnetic resonance imaging (MRI), FDG-PET, DAT-PET, and 18F-Florbetaben (FBB) PET scans at the dementia and movement clinics of Yonsei University Severance Hospital, Seoul, Korea from November 2015 to March 2019. Ten control subjects did not undergo FBB-PET. Clinical features of DLB, including parkinsonism, rapid eye movement sleep behavior disorder (RBD), visual hallucinations, and cognitive fluctuation, were evaluated based on structured questionnaires administered by caregivers. The severity of parkinsonism was assessed according to the Movement Disorder Society’s Unified…
