The development of dementia late in life, often from Alzheimer’s disease, is associated with abnormal blood levels of dozens of proteins up to five years earlier, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Most of these proteins were not known to be linked to dementia before, suggesting new targets for prevention therapies.
The findings are based on new analyses of blood samples of over ten thousand middle-aged and elderly people—samples that were taken and stored during large-scale studies decades ago as part of an ongoing study. The researchers linked abnormal blood…
