Newswise — Rockville, Md. – New research shows retinal cell types are vulnerable to Alzheimer’s pathology, suggesting retinal function may be useful in predicting and diagnosing changes in the brain with Alzheimer’s disease. This study will be presented during the 2021 Annual Meeting of The Association for Research in Vision and Ophthalmology (ARVO), being held virtually this year.
Alzheimer’s disease, which currently affects 24 million people worldwide, is a disease characterized by accumulation of amyloid-beta plaques and neurofibrillary tangles of Tau protein in the brain, associated with neurodegeneration and deficits in memory and cognition. Retinal pathology has been reported with Alzheimer’s disease as well.
Led by Rachael S. Allen, PhD, at the Atlanta VA Medical Center, the research team worked to determine whether the TgF344-AD transgenic rat model (n=7)…
