Biomarker Use for Dementia With Lewy Body Diagnosis: Survey of US Experts

imageBackground:

Dementia with Lewy body (DLB) diagnostic criteria define “indicative” and “supportive” biomarkers, but clinical practice patterns are unknown.

Methods:

An anonymous survey querying clinical use of diagnostic tests/biomarkers was sent to 38 center of excellence investigators. The survey included “indicative” biomarkers (dopamine transporter scan, myocardial scintigraphy, polysomnography), “supportive” biomarkers [magnetic resonance imaging (MRI)], positron emission tomography, or single-photon emission computed tomography perfusion/metabolism scans, quantitative electroencephalography), and other diagnostic tests (neuropsychological testing, cerebrospinal fluid analysis, genetics). Responses were analyzed descriptively.

Results:

Of the 22 respondents (58%), all reported the capability to perform neuropsychological testing, MRI,…

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