Mice
All animal procedures followed the Canadian Council on Animal Care guidelines and were approved by the animal care committees of McGill University (protocols #2009-5727, #2011-6027, and #2016-779) and Université de Montréal (protocol #19-045). Experimental mice were generated and aged at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal pathogen-free animal facility, and transferred to the Lady Davis Institute (LDI) animal facility for behavioural experiments two weeks before experiments for adjustment to a reverse light cycle. Animals were group-housed (2-3 animals per cage) in standard macrolon cages (40 × 25 × 20 cm) with contact bedding (7907, Envigo Teklad Lachine, QC, Canada), one Nestlet® (NES3600, Ancare Corporation, Bellmore, NY, USA) and one cardboard house (XKA2455, Ketchum manufacturing, Brockville, ON, Canada)…
