A unique brain protein measured in the blood could be used to diagnose Alzheimer’s disease decades before symptoms develop, according to new Edith Cowan University (ECU) research.
Published in Nature journal Translational Psychiatry, the study is the first to find that people with elevated glial fibrillary acidic protein (GFAP) in the blood also have increased amyloid beta in the brain, a known indicator of Alzheimer’s disease.
GFAP is a protein normally found in the brain, but it is released into the blood when the brain is damaged by early Alzheimer’s disease.
Alzheimer’s disease affects more than 340,000 Australians and more than 35 million people in the world. Current diagnosis involves a brain scan or spinal fluid tests.
The study’s lead researcher, ECU Professor Ralph Martins AO, said the discovery offered a promising new avenue for early diagnosis.
“Blood biomarkers are…