Genetic study of Lewy body dementia supports ties to Alzheimer’s and Parkinson’s diseases

Genetic study of Lewy body dementia supports ties to Alzheimer's and Parkinson's diseases
An NIH-led genetic study found that Lewy body patients had higher chances of suffering Alzheimer’s or Parkinson’s disease than age-matched controls. Credit: Courtesy of Scholz lab NIH/NINDS.

In a study led by National Institutes of Health (NIH) researchers, scientists found that five genes may play a critical role in determining whether a person will suffer from Lewy body dementia, a devastating disorder that riddles the brain with clumps of abnormal protein deposits called Lewy bodies. Lewy bodies are also a hallmark of Parkinson’s disease. The results, published in Nature Genetics, not only supported the disease’s ties to Parkinson’s disease but also suggested that people who have Lewy body dementia may share similar genetic profiles to those who have Alzheimer’s disease.

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