A City of Hope-led research team found that the same gene that increases the risk for Alzheimer’s disease, ApoE4, can increase the susceptibility to and severity of COVID-19.
“Our study provides a causal link between the Alzheimer’s disease risk factor ApoE4 and COVID-19 and explains why some (e.g., ApoE4 carriers) but not all COVID-19 patients exhibit neurological manifestations” said Yanhong Shi, Ph.D., director of the Division of Stem Cell Biology at City of Hope and co-corresponding author of the…