Memory deficits resulting from epigenetic changes in Alzheimer’s disease can be reversed

Memory deficits resulting from epigenetic changes in Alzheimer's disease can be reversed
Photo illustration: UB co-authors of the Science Advances paper are L to R: Jamal Williams, doctoral candidate; Zhen Yan, PhD, SUNY Distinguished Professor and senior author and Qing Cao, PhD, postdoctoral fellow and first author. (Individuals were photographed separately.) Credit: Douglas Levere/University at Buffalo

Memory loss associated with Alzheimer’s disease (AD) may be able to be restored by inhibiting certain enzymes involved in abnormal gene transcription, according to a preclinical study by researchers at the University at Buffalo. The findings could pave the way toward new treatments for Alzheimer’s disease.

The paper will be published on Dec. 9 in…

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