Virginia Tech scientists advance understanding of blood-brain barrier health

Newswise — Hard skulls help protect our brains from physical injuries. 

In addition to a tough outer shell, brains have internal defenses, including a powerful shield called the blood-brain barrier that defends brain cells from substances in the bloodstream that are toxic and dangerous to nerve cells. If the blood-brain barrier is breached, then health problems arise.

Now, in a study with potential impacts on a variety of neurological diseases, Virginia Tech researchers have provided the first experimental evidence from a living organism to show that an abundant, star-shaped brain cell known as an astrocyte is essential for blood-brain barrier health.

The research in today’s (Monday, Sept. 21) online edition of the journal GLIA reassesses traditional claims about the role of astrocytes in the brain and confirms the long-held assumption — although it had been recently…

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