Decoding the genetics that drive disease

Decoding the genetics that drive disease
Some human genes traditionally labeled as ‘bad’ are not always what they seem. Credit: Gerd Altmann from Pixabay

From Alzheimer’s to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labeled as ‘bad’ are not always what they seem.

Examining the three main variants (ε4, ε3, and ε2) of the apolipoprotein E (APOE) gene involved in the metabolism of fats in the body—researchers found that both the typically ‘bad’ variant, APOE ε4, and the ‘good’…

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