A drug used to treat cirrhosis of the liver may be an effective treatment for a form of Dementia and motorneuron disease, scientists have discovered.
The research, led by the University of York in collaboration with the University of Sheffield, used brain cells from fruit flies and rats to model the neurodegeneration process which occurs in patients with Frontotemporal Dementia (FTD).
The researchers identified new proteins involved in protecting neurons and discovered that Ursodeoxycholic Acid—an already approved drug, with very low toxicity—increases these proteins and protects neurons from death.
The authors of the study will now…