Alzheimer’s disease (AD) is the most common form of dementia among the elderly and currently there is no cure for the disease. The hallmarks of AD are the Aβ plaques and tau tangles found throughout the patient’s brain. For the past several decades, much of the work to find a treatment for AD has been focused on eliminating those dreaded Aβ plaques, by assuming that memory could be restored by removing the plaques.
“Unfortunately, clinical trials on this attempt have repeatedly failed,” said Ai-Ling Lin, associate professor at the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) and UK College of Medicine.
Lin…