Genes and cardiovascular health each contribute in an additive way to a person’s risk of dementia, U.S. researchers including Sudha Seshadri, MD, and Claudia Satizabal, Ph.D., of The University of Texas Health Science Center at San Antonio (UT Health San Antonio) reported July 20 in the journal Neurology.
The study was conducted in 1,211 participants in the Framingham Heart Study and involved collaborators from Boston University.
Participants with a high genetic risk score based on common genetic variants, including having an allele called apolipoprotein E (APOE) ε4, were at a 2.6-fold higher risk of developing dementia than subjects…