Brain network mechanism causing spatial memory impairment revealed

Brain network mechanism causing spatial memory impairment revealed
New study, led by UCI School of Medicine’s Kei Igarashi, PhD, found that remapping of place cells, a brain circuit function to discriminate distinct environments, was disrupted in Alzheimer’s disease mice. Credit: UCI School of Medicine

July 21, 2020—Patients with Alzheimer’s disease frequently suffer from spatial memory loss, such as no recognition of where they are, and forgetting where they put their belongings. They often show a wandering symptom, which is also a feature of spatial memory impairment. Until now, the brain network mechanism that causes spatial memory impairment had been unclear.

Published today in Neuron, the study titled, “Disrupted place…

Read more…