Abnormal proteins in the gut could contribute to the development of Alzheimer’s disease

Alzheimer's disease
PET scan of a human brain with Alzheimer’s disease. Credit: public domain

A new study published in the Journal of Physiology has shown that misfolded protein build-up in the gut could contribute to the development of Alzheimer’s-like symptoms in mice. This could suggest a new treatment approach for Alzheimer’s disease that would target the gut before symptoms of cognitive deficits appear in patients.

As these proteins were found in the gut, which is a window to the world, this suggests might be contributing to cognitive deficits seen in Alzheimer’s disease and other conditions.

The misfolded protein, known to be involved in Alzheimer’s disease, called , was injected…

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