Why Do More Women Have Alzheimer’s than Men? It’s Not Just from Living Longer

 

Newswise — MINNEAPOLIS – Middle-aged women are more likely than men to have changes in the brain related to Alzheimer’s disease, as detected by imaging, even when there are no differences in thinking and memory. This may be associated with hormonal changes due to menopause, specifically the loss of estrogen, according to a study published in the June 24, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.

“About two-thirds of people living with Alzheimer’s are women, and the general thinking has been it’s because women tend to live longer,” said study author Lisa Mosconi, Ph.D., of Weill Cornell Medicine, New York, N.Y. “Our findings suggest that hormonal factors may predict who will have changes in the brain. Our results show changes in brain imaging features, or biomarkers in the brain, suggesting menopausal…

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