Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells—a potential advance in the fight against Alzheimer’s disease.
Their method is able to recognise these toxic particles, known as amyloid-beta oligomers, which are the hallmark of the disease, leading to hope that new diagnostic methods can be developed for Alzheimer’s disease and other forms of dementia.
The team, from the University of Cambridge, University College London and Lund University, designed an antibody which is highly accurate at detecting toxic oligomers and quantifying their numbers. Their…
