Newswise — Irvine, CA – May 12, 2020 – A team of researchers from the University of California, Irvine and San Diego have been awarded $3.8 million by the National Institute on Aging to conduct an epigenomic analysis of neural circuits in the brain. By revealing molecular changes that occur during the course of Alzheimer’s disease (AD), the team hopes to identify new therapeutic targets and molecular biomarkers for early detection and better treatment.
The interdisciplinary research team is led by multiple principal investigators, including Xiangmin Xu, PhD, a professor of anatomy and neurobiology and director of the Center for Neural Circuit Mapping at the UCI School of Medicine, Carl Cotman, PhD, a professor of neurology and founding director of the Institute for Brain Aging and Dementia at the UCI School of Medicine, and Bing Ren, PhD, a professor of cellular and…