A meta-analysis of gene expression data highlights synaptic dysfunction in the hippocampus of brains with Alzheimer’s disease

  • 1.

    Selkoe, D. J. & Hardy, J. The amyloid hypothesis of Alzheimer’s disease at 25 years. EMBO molecular medicine 8, 595–608 (2016).

  • 2.

    Association, A. s. 2019 Alzheimer’s disease facts and figures. Alzheimer’s & Dementia 15, 321–387 (2019).

  • 3.

    Li, X., Long, J., He, T., Belshaw, R. & Scott, J. Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease. Scientific reports 5, 12393 (2015).

  • 4.

    Puthiyedth, N., Riveros, C., Berretta, R. & Moscato, P. Identification of differentially expressed genes through integrated study of Alzheimer’s disease affected brain regions. PLoS One 11, e0152342 (2016).

  • 5.

    Moradifard, S., Hoseinbeyki, M., Ganji, S. M. & Minuchehr, Z. Analysis of microRNA and Gene Expression Profiles in Alzheimer’s Disease: A Meta-Analysis Approach. Scientific reports 8, 4767 (2018).

  • 6.

    Patel, H., Dobson, R. J. & Newhouse,…

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