When tested in brain cells and in a mouse model of Alzheimer’s disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of the disease.
The researchers who developed the compound report their findings in the journal ACS Chemical Neuroscience.
Amyloid plaques are a hallmark of Alzheimer’s disease in the brain, as is the accumulation of a protein known as p-tau, said Liviu Mirica, a chemistry professor at the University of…
