Engineers and scientists led by Tufts University used a three-dimensional (3-D) human tissue culture model mimicking the components and conditions in the brain to demonstrate a possible causal relationship between sporadic Alzheimer’s disease and herpes simplex virus I infection (HSV-1). Reported today in Science Advances, the model will allow for further studies into the causes and possible treatments of this devastating neurodegenerative condition.
After infecting neurons in the bioengineered brain…