In patients with both amyotrophic lateral sclerosis and frontotemporal dementia (ALS–FTD), the initial presenting symptoms can provide clues as to the future trajectory of the disease, according to new research published in Neurology.
“We wanted to investigate whether disease progression in patients with ALS–FTD differed depending on whether they present first with motor or cognitive symptoms,” explains corresponding author Rebekah Ahmed. “This question has implications for prognostication and also for disentangling fast and slow progressors in clinical trials.”
The study included 59 patients with ALS–FTD who were recruited from…
