Participants
We retrospectively collected data from 226 patients with amyloid PET-positive AD and 17 patients with amyloid PET-positive lvPPA. Experienced neurologists evaluated the participants based on their clinical symptoms and reviewed medical histories, neuropsychological test results, MRI, amyloid PET, and laboratory tests. AD patients met the research criteria for probable AD dementia with evidence of the AD pathophysiological process proposed by the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association (NINCDS-ADRDA)1. lvPPA patients met current consensus criteria for lvPPA18. Participants with other structural lesions, such as territorial infarction, intracranial hemorrhage, brain tumor, hydrocephalus, or severe white matter hyperintensities (WMH), observed on brain MRI were excluded. Severe…
