Reducing early brain inflammation could slow Alzheimer’s progression

Reducing early brain inflammation could slow Alzheimer's progression
This fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of Rome

In a new animal study examining Alzheimer’s disease, researchers found that disease progression could be slowed by decreasing neuroinflammation in the brain before memory problems and cognitive impairment were apparent. The new findings point to the importance of developing therapies that target very early stages of the disease.

In 2011, the National Institute on Aging updated the for Alzheimer’s to reflect its progressive nature. The criteria added a preclinical stage during which brain changes are…

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