Amyloid plaque formation directly causes brain tissue loss in animals, but a drug called lithium reduces the life-shortening effects of this loss, shows a study published today in eLife.
Patients with Alzheimer’s disease experience progressive memory loss and loss of brain matter over time. This study provides new details about what happens in the brain in Alzheimer’s disease and suggests a potential strategy to slow it.
Both the production of small protein fragments called Amyloid-ß and the assembly of these fragments into large clusters or plaques have been implicated in Alzheimer’s disease. But teasing apart the role of Amyloid-ß versus the role of plaque formation has…
