Scientists at the German Center for Neurodegenerative Diseases (DZNE), the Ludwig-Maximilians-Universitaet (LMU) Munich and Denali Therapeutics (South San Francisco, CA, U.S.) have developed an approach to stimulate immune cells of the brain in such a way that they might possibly provide better protection against Alzheimer’s disease. Their report has been published in the journal EMBO Molecular Medicine. These findings could ultimately enable development of novel therapies to treat Alzheimer’s disease.
The researchers identified a specific antibody that binds to the brain’s immune cells, the microglia. The antibody stimulates their activity in such a way that they live…