Willingness to Undergo a Risky Treatment to Improve Cognition Among Persons With Cognitive Impairment Who Received an Amyloid PET Scan

Objective:
To evaluate determinants of willingness to accept a treatment to return memory to normal among persons with cognitive impairment who received an amyloid positron emission tomography (PET) scan and their care partner and discordance in risk taking.
Methods:
Using data from CARE-IDEAS (n=1872 dyads), a supplement of the Imaging Dementia–Evidence for Amyloid Scanning study, we predicted scan recipient’s willingness to accept a risky treatment, the risk care partners believed their care recipient would accept, and discordance in these perceptions.
Results:
Scan recipients were willing to accept a treatment with a 27.94% (SD=34.36) risk of death. Care partners believed their care recipient would accept a 29.68% (SD=33.74) risk of death; thus, overestimating risk acceptance by 1.74 (SD=41.88) percentage points. A positive amyloid PET scan was associated with…

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