New research has shed fresh light on how the build-up of two proteins in the brain might affect the activity of genes involved in Alzheimer’s disease.
Researchers at the University of Exeter worked in collaboration with Eli Lilly and Company to examine the brains of mice carrying mutations in the genes for the proteins amyloid and tau. The build-up of both proteins in specific regions of the brain is known to play a role in Alzheimer’s disease.
In a paper published today in Cell Reports, the researchers found evidence that the levels of gene activity changed dramatically as tau and amyloid accumulated in the brain. The…
