Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration

By
dementianews
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The goal of this analysis was to characterize cognitive performance, behavioral ratings, and brain volumes in a large group of f-FTLD family members. In group comparisons, asymptomatic mutation carriers showed nearly identical scores on all clinical measures compared with noncarriers but reduced frontal and temporal lobe volumes. The group with mild/questionable impairment showed decreased story recall, word list…

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