Many patients with iNPH develop Alzheimer’s disease, too

brain
Credit: CC0 Public Domain

Up to one in five patients treated for idiopathic normal pressure hydrocephalus, iNPH, also develop Alzheimer’s disease, according to a new study from the University of Eastern Finland and Kuopio University Hospital. The researchers were able to predict the development of Alzheimer’s disease by using the Disease State Index, DSI, that combines patient-specific data from various sources. The results were published in Journal of Alzheimer’s Disease.

In iNPH, the circulation of cerebrospinal fluid (CSF) is disturbed for an unknown reason, leading to a slightly elevated brain pressure and dilation of the brain ventricles. Symptoms of NPH include gait deviations, impaired

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