Rapamycin prevents age-related brain vascular deterioration

brain
Credit: CC0 Public Domain

A just-released study by UT Health San Antonio and collaborating institutions shows age-related decreases in blood flow to the brain and memory loss can be modified with the drug rapamycin.

This finding, if furthered, holds implications for aging in general and perhaps offers an avenue to prevent Alzheimer’s dementia in some people, said research first author Candice Van Skike, Ph.D., of UT Health San Antonio.

In the study, published Nov. 6 in the journal Aging Cell, researchers began rats on a diet including low-dose rapamycin at 19 months old (past middle age in rat years). Rapamycin treatment in daily food continued until the mice were of advanced age—34 months…

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