Do Alzheimer’s and Lewy body disease have discrete pathological signatures of gait?

Jump to Section1. Objective2. Introduction3. Updated hypothesis  3.1. Early experimental data—Methods    3.1.1. Participants    3.1.2. Ethical considerations    3.1.3. Clinical assessment    3.1.4. Cognitive assessment    3.1.5. Gait assessment    3.1.6. Data analysis  3.2. Early experimental data—Results    3.2.1. Study participants and demographics    3.2.2. Differences in gait impairments between AD and LBD    3.2.3. Gait impairments in dementia subtypes compared with controls    3.2.4. Explanatory variables of discrete gait impairments in dementia subtypes  3.3. Future experiments and validation studies4. Major challenges for the hypothesis5. Linkage to major theories  5.1. Associations between discrete gait and cognitive impairments reflect neuropathological change  5.2. Gait could act as proxy measure for neuropathology6….

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