A novel kit for early diagnosis of Alzheimer’s disease using a fluorescent nanoparticle imaging

Physical and binding properties of the diagnostic kit

Studies have been conducted to develop diagnostic indices for the early detection of AD³⁵. Our fluorescent nanoparticle complex for detecting miRNA and antigens for the early detection of AD has the following properties and structure.

First, the molecules of structures I and II form a fluorescent nanoparticle complex for AD-specific miRNA detection and have a structure of A-B-C1-B’-Z (Fig. 1A).

The development of the WO2002/088706 fluorescent nanoparticle kit and application of the nanoparticles. Figure illustrating the structure of a probe complex according to the design for this study. Figure showing the state in which fluorescent nanoparticles are bound to regions that can be dissociated when binding to specific target molecules in samples such as nerve cells, tissues or plasma. The figure also illustrates the overall…