Scientists rethink Alzheimer’s, diversifying the drug search

Scientists rethink Alzheimer's, diversifying the drug search
In this Aug. 14, 2019 photo provided by the University of Kentucky, Donna Wilcock, of the Sanders-Brown Center on Aging, holds a brain in her lab in Lexington, Ky. She says that contrary to popular perception, “there are a lot of changes that happen in the aging brain that lead to dementia in addition to plaques and tangles.” (Mark Cornelison/University of Kentucky via AP)

When researchers at the University of Kentucky compare brains donated from people who died with dementia, very rarely do they find one that bears only Alzheimer’s trademark plaques and tangles—no other damage.

If they do, “we call it a unicorn,” said Donna Wilcock, an Alzheimer’s specialist at the university’s aging center….

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