Patients with mild Alzheimer’s have had a deep brain stimulation (DBS) system implanted in this study to evaluate the safety and potential clinical benefit of DBS of the fornix (DBS-f), a major inflow and output pathway in the brain’s memory circuit. The ADvance Study is the only double-blind randomized and controlled trial and the largest study ever conducted of DBS for Alzheimer’s. Top-line outcomes data are expected in the second quarter of 2015.
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Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
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